Melatonin in the complex treatment of gastro esophageal reflux disease in children

This article deals with the problem of gastroesophageal reflux disease (GERD) in children, which has an enormous medical and social importance. Despite recent advances in therapy, the disease is characterized by recurrent exacerbations with the development of complications, which dictates the need of finding a new pathogenically supported esophagitis treatment. In this regard, the effectiveness of melatonin was evaluated in the treatment of the gastroesophageal reflux disease in 20 patients. During the intake of this medicine a clear positive trend was set, which included: the elimination of pain, lack of palpable pain in the epigastria and pyloric duodenal areas, reduction of the frequency of dyspeptic symptoms, a significant reduction in gastroesophageal reflux during dynamic endoscopic examination, and improvements of the function of gastric acid, regulatory processes in the digestive tract due to the normalization of melatonin levels. Scientific evidence shows that the inclusion of the drug in the complex treatment of GERD patients can improve the effectiveness of therapy by 2.5 times.